MacroDesign

MacroDesign

Bridging wet lab experimentation and computational design for next-generation macromolecules

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Our Mission

MacroDesign is a collaborative initiative that brings together experimental biologists and computational scientists to revolutionize macromolecule design through integrated approaches.

We aim to accelerate the discovery and optimization of novel proteins, nucleic acids, and other macromolecules for applications in medicine, materials science, and biotechnology.

By combining cutting-edge wet lab techniques with advanced computational methods, we're creating a seamless pipeline from in silico design to experimental validation and refinement.

Scientists collaborating on macromolecule design

Our Collaborative Teams

Wet Lab Team
Experimental biology and biochemistry

  • Protein Expression & Purification

    High-throughput expression and purification of designed macromolecules

  • Structural Characterization

    X-ray crystallography, cryo-EM, and NMR analysis of macromolecular structures

  • Functional Assays

    Comprehensive testing of binding, catalytic activity, and stability

Dry Lab Team
Computational modeling and design

  • Molecular Dynamics

    Advanced simulation of macromolecular behavior and interactions

  • Structure Prediction

    AI-powered prediction of protein folding and docking interactions

  • Literature Mining

    Automated extraction and analysis of published research findings

Collaborative Institutions

Partner 1
Partner 2
Partner 3
Partner 4

Our Software Platform

An integrated suite of computational tools for macromolecule design, analysis, and optimization

Molecular Dynamics Pipeline

Our molecular dynamics platform enables high-throughput simulation of macromolecular behavior under various conditions.

  • 1
    Force field selection and parameterization
  • 2
    System preparation and solvation
  • 3
    Energy minimization and equilibration
  • 4
    Production simulation with GPU acceleration
  • 5
    Trajectory analysis and visualization
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Molecular dynamics simulation interface

Published Research

Our platform integrates the latest findings from scientific literature to inform macromolecule design

Current Projects

Explore our ongoing research initiatives and their progress

Join Our Collaboration

We're always looking for new partners, researchers, and institutions to join our collaborative effort in macromolecule design.

Become a Partner